בשל "הגנת זכויות יוצרים" מובא להלן קישור לתקציר המאמר. לקריאתו בטקסט מלא, אנא פנה/י לספרייה הרפואית הזמינה לך.

  Clear surgical margins reduce the risk of local recurrence, improve survival, and determine decision-making with regard to adjuvant treatment of squamous cell carcinoma of the head and neck (SCCHN).

However, the definitions of clear, close, or positive surgical margins vary in both the literature and in practice.

We examine whether the association between surgical margin distance and survival varies by primary tumor site.

This was a secondary analysis of a multi-institutional, multinational randomized clinical trial.

The trial enrolled patients from January 22, 2007, to March 29, 2013, with stage II to IVA resected SCCHN with extranodal extension (ENE) or positive margins (<5 mm from invasive tumor to the resected margin).

The current analysis included those patients with known ENE and margin status and was conducted from April 29, 2022, to December 19, 2022.