There is a link between laryngopharyngeal reflux (LPR) and the formation of benign vocal fold lesions (BVFLs).

However, previous studies have mainly focused on LPR suggested by symptoms and signs, rather than objectively diagnosed LPR via pharyngeal pH monitoring.

We, therefore, conducted a Meta-analysis to evaluate the association between pharyngeal pH monitoring diagnosed LPR and the odds of BVFLs.

Relevant observational studies were identified by searching PubMed, Embase, Cochrane Library, and Web of Science.

We evaluated between-study heterogeneity using the Cochrane Q test and estimated the I2 statistic.

Random-effects models were used when significant heterogeneity was observed; otherwise, fixed-effects models were used.